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M94A0692.TXT
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1994-10-21
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Document 0692
DOCN M94A0692
TI Long term asymptomatic infection in six blood transfusion recipients
with a single common donor.
DT 9412
AU Learmont J; Tindall B; Sullivan J; Dwyer D; Cunningham A; Wylie B; Red
Cross Blood Transfusion Service NSW.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:35 (abstract no. SC3).
Unique Identifier : AIDSLINE ASHM5/94348963
AB OBJECTIVES: To investigate the possibility of any additional recipients
from the common donor and to further describe the health status of the
group. RESULTS: 7 more donations were identified and 4 recipients traced
and tested. 3 recipients of 1980 donations tested negative. A 77 year
old female transfused in April 1981 tested anti-HIV positive. She is
asymptomatic, with conserved CD4+ count, 12 years since transfusion. The
asymptomatic group have been reviewed an average of 8.5 years following
infection. They are PCR positive, all remain clinically asymptomatic
with conserved CD4 counts and none have received anti-viral therapy.
CONCLUSION: The identification of yet another asymptomatic recipient
from a single common donor, 12 years since infection, and the continued
asymptomatic status of the group strongly suggests that the donor and
the new hosts have all been infected with a relatively non-virulent
strain of HIV-1.
DE Aged *Blood Donors *Blood Transfusion Case Report Female Follow-Up
Studies Human HIV Seropositivity/DIAGNOSIS/*TRANSMISSION
HIV-1/PATHOGENICITY Leukocyte Count Polymerase Chain Reaction T4
Lymphocytes/IMMUNOLOGY Virulence MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).